Thursday, February 7, 2013

Gail Collins, "My Kingdom for a Corpse": Bored to Tears, Collins Rekindles War of the Reeking Roses with Donald Trump

Based upon the discovery of a skeleton with a deformed spinal column coupled with sophisticated DNA analysis, archaeologists have conclusively determined that they have unearthed the remains of England's King Richard III ("My kingdom for a horse") under a Leicester parking lot.

With nothing better to write about, Gail Collins, in her latest New York Times op-ed entitled "My Kingdom for a Corpse" (http://www.nytimes.com/2013/02/07/opinion/collins-my-kingdom-for-a-corpse.html?_r=0), has seized upon this memorable occasion to rekindle her war of words with Donald Trump. You will recall that Trump once circled a picture of Collins, wrote "The Face of a Dog!" over it, and sent it over to Gail (see: http://www.huffingtonpost.com/2011/04/09/donald-trump-gail-collins-new-york-times_n_847015.html).

In her opinion piece of today's date, Collins writes:

"In 2313, maybe the Donald Trump Society will dig up the real estate developer and discover that he had a really terrific head of hair. There’s hope for us all. We may be wrinkling now, but we’ll look great in a few more millennia."

Well, let's fast forward ten more years:

Manhattan, 2323 - Archaeologists, digging under the ruins of the New York Times Building in Manhattan, have discovered the well-preserved bodies of Andrew Rosenthal, Thomas Friedman and Gail Collins, surrounded by a mountain of mildewing bonbons. It is believed that the combined weight of Rosenthal, Friedman and Collins caused the collapse of the skyscraper, owing to its decaying infrastructure.

The discovery of the bodies in the proximity of the bonbons laid to rest speculation, set in motion by Times columnist Nicholas Kristof, that the corpulence of Rosenthal, Friedman and Collins had resulted from lounging on sofas suffused with endocrine-disrupting chemicals.

C'est tout.

Tuesday, February 5, 2013

Thomas Friedman, "India vs. China vs. Egypt": King Kong vs. Godzilla vs. Mothra

Consider: The United States, with more than $16.4 trillion in debt, continues to borrow from a repressive regime in China, while funding Egypt's military to the tune of $1.3 billion each year. The US, of course, is attempting to isolate Iran as it proceeds pell-mell with its nuclear weapons development program, so it should come as no surprise that yesterday, Egyptian president Morsi ("the Jews are descendants of apes and pigs") hosted Iranian president Ahmadinejad ("Israel must be wiped off the map") in Cairo, representing the first visit by an Iranian leader to Egypt in decades. In parallel, Obama is attempting to paint the transition of Egypt from the Mubarak regime to a government headed by the extremist Muslim Brotherhood as a success: "You know, when it comes to Egypt, I think, had it not been for the leadership we showed, you might have seen a different outcome there" (http://www.cbsnews.com/8301-18560_162-57565734/obama-and-clinton-the-60-minutes-interview/?pageNum=5).

What does any of the above have to do with the price of tea in China?

In his latest New York Times op-ed entitled "India vs. China vs. Egypt" (http://www.nytimes.com/2013/02/06/opinion/friedman-india-vs-china-vs-egypt.html?_r=0), Thomas Friedman, still dilly-dallying in New Delhi, would compare the futures of India, China and Egypt. In this regard, Friedman writes:

"'India today has 560 million young people under the age of 25 and 225 million between the ages of 10 and 19,' explained Shashi Tharoor, India’s minister of state for human resource development. 'So for the next 40 years we should have a youthful working-age population' at a time when China and the broad industrialized world is aging. According to Tharoor, the average age in China today is around 38, whereas in India it’s around 28. In 20 years, that gap will be much larger. So this could be a huge demographic dividend — 'provided that we can educate our youth — offering vocational training to some and university to others to equip them to take advantage of what the 21st-century global economy offers,' said Tharoor. 'If we get it right, India becomes the workhorse of the world. If we get it wrong, there is nothing worse than unemployable, frustrated' youth."

Indeed, China is headed for an iceberg. China has sought to check population growth with its one-child per family policy; however, will China's youth ultimately be able to support a growing percentage of seniors? And then there is also the question concerning the ultimate value of the debt denominated in dollars owed to China by the US, should America's budget deficit continue to go unchecked in the decades to come.

Egypt, now with less than $15 billion in foreign reserves, poverty, illiteracy, daily rioting, discrimination against women most of whom have had their genitals mutilated, oppression of its Christian Coptic minority, and a population that is growing beyond the country's means, is headed for disaster.

"India vs. China vs. Egypt"? My bet is on India, but I am far more concerned with events in the US and the absence of a cogent economic policy.

Meanwhile, this has given me the inspiration to begin writing yet another failed screenplay: "King Kong vs. Godzilla vs. Mothra." Who do you think wins in the end? Yeah, I know, who cares? I also have more pressing problems at home.

Ahmadinejad and Morsi: Two Jew-Haters Meet in Cairo

Currently, the US is attempting to isolate Iran as it proceeds pell-mell with its nuclear weapons development program. In parallel, Obama is attempting to paint the transition of Egypt from the Mubarak regime to a government headed by the extremist Muslim Brotherhood as a success ("You know, when it comes to Egypt, I think, had it not been for the leadership we showed, you might have seen a different outcome there," http://www.cbsnews.com/8301-18560_162-57565734/obama-and-clinton-the-60-minutes-interview/?pageNum=5).

So, it should come as no surprise that Egyptian president Morsi ("the Jews are descendants of apes and pigs") yesterday hosted Iranian president Ahmadinejad ("Israel must be wiped off the map") in Cairo, representing the first visit by an Iranian leader to Egypt in decades.

Meanwhile, the US continues to provide Egypt with more than a billion dollars of military aid annually (see: http://www.haaretz.com/news/diplomacy-defense/u-s-approves-1-3-billion-dollars-in-military-aid-to-egypt-1.420447).

Will the Obama administration continue to fund the Egyptian army as Egypt draws nearer to Iran? Was there ever any doubt?

Monday, February 4, 2013

David Brooks, "The Philosophy of Data": Ignoring Life Sciences, Brooks Is at Sea in an Ocean of Data

In his latest New York Times op-ed entitled "The Philosophy of Data" (http://www.nytimes.com/2013/02/05/opinion/brooks-the-philosophy-of-data.html?_r=0), David Brooks describes what he labels "data-ism," which, he says, is "the rising philosophy of the day." Brooks writes:

"We now have the ability to gather huge amounts of data. This ability seems to carry with it certain cultural assumptions — that everything that can be measured should be measured; that data is a transparent and reliable lens that allows us to filter out emotionalism and ideology; that data will help us do remarkable things — like foretell the future."

Brooks goes on to show how data can be used to show that "our intuitive view of reality is wrong," for example, with regard to basketball foul shooting, the effectiveness of political campaign spending, and the relationship between the use of the world "I" and self-confidence.

However, Brooks nowhere mentions the vast amounts of data being accumulated by the life sciences.

I am privileged to work as an outside consultant to Compugen, which is revolutionizing the manner in which new drugs and diagnostics are discovered, and which has spent the past decade building an infrastructure of proprietary scientific understandings, predictive platforms, algorithms, and machine learning systems for the in silico (by computer) prediction and selection of product candidates.

In a recent press release (http://cgen.com/press-releases/189-compugen-announces-development-of-nexgen-infrastructure-platform-for-analysis-of-next-generation-sequencing-data), Compugen described a new infrastructure platform that it had created for the analysis of massive quantities of next generation sequencing data to enhance the company's infrastructure for predictive drug and drug target discovery:

"The high demand for low-cost sequencing has provided strong incentives to develop 'next generation sequencing' technologies. These technologies rely on various methods to parallelize the sequencing process, thus producing millions of sequences simultaneously, with exceptional speed, yield and specificity. Such high-throughput sequencing technologies, known as parallel deep sequencing technologies, are lowering the cost and increasing the output of DNA and RNA sequencing (RNA-Seq) by orders of magnitude beyond what is possible with standard dye-terminator methods. Furthermore, these technologies in theory should facilitate various types of analysis, such as transcriptome analyses, de-novo assembly of genomes, identification of single nucleotide DNA mutations, and more. However, the massive amount of raw data generated in this form also imposes huge analytical challenges to obtain meaningful and accurate information."

In short, the life sciences are creating oceans of data, and the primary challenge is no longer collection, but rather analysis.

New insights regarding foul shooting percentages? Quite honestly, I don't particularly care. Of far greater significance is our proximity to deciphering billions of years of evolution and the complexity of life, resulting in new medicines and diagnostics for unmet medical needs.

Now if we can only prevent ourselves from destroying the planet as this revolution in life sciences, premised upon unprecedented data collection and analytical capabilities, unfolds.

[As noted in prior blog entries, I am a Compugen shareholder, this blog entry is not a recommendation to buy or sell Compugen shares, and in September 2009 I began work as a part-time external consultant to Compugen. The opinions expressed herein are mine and are based on publicly available information. This blog entry has not been authorized, approved or reviewed prior to posting by Compugen.]

You Want to Know More About the Middle East Than John Kerry? Easy!

So, you want to know more about recent events in the Middle East than John Kerry, America's new secretary of state, who once referred to Syrian mass murderer Bashar al-Assad as his "dear friend"? What could possibly be easier?

Tomorrow, over cocktails in Foggy Bottom, you can regale your friends and befuddle your enemies with the following information:

Let me know if that doesn't have them agog. No cocktails for me. It's my wedding anniversary, and I need to be reminded of what I did wrong this past year. A bit like a second day of atonement. Think of me kindly as you sip your Manhattans.

"Yes, dear. Coming, dear."




Sunday, February 3, 2013

Paul Krugman, "Friends of Fraud": Do You Own Shares?

It's only the Republicans who are "defrauding" the public? Yeah, right.

In his latest New York Times op-ed entitled "Friends of Fraud" (http://www.nytimes.com/2013/02/04/opinion/krugman-friends-of-fraud.html?_r=0), Paul Krugman complains that Republicans are "threatening to filibuster the appointment of Richard Cordray, the [Consumer Financial Protection Bureau's] acting head, and thereby leave the bureau unable to function." Krugman concludes:

"Right now, all the media focus is on the obvious hot issues — immigration, guns, the sequester, and so on. But let’s try not to let this one fall through the cracks: just four years after runaway bankers brought the world economy to its knees, Senate Republicans are using every means at their disposal, violating all the usual norms of politics in the process, in an attempt to give the bankers a chance to do it all over again."

The Consumer Financial Protection Bureau? A fine idea, but it's the repeal of the Uptick Rule, for which Republicans and Democrats are both responsible, which is allowing financial institutions to milk the American public and destroying the US economy.

Given the importance of the subject, I will again repeat myself:

The Uptick Rule went into effect in 1938 in response to market abuses that threatened the health of the US economy and prohibited short sales of securities except on an "uptick." As summarized by the SEC:

"Rule 10a-1(a)(1) provided that, subject to certain exceptions, a listed security may be sold short (A) at a price above the price at which the immediately preceding sale was effected (plus tick), or (B) at the last sale price if it is higher than the last different price (zero-plus tick). Short sales were not permitted on minus ticks or zero-minus ticks, subject to narrow exceptions."

The Uptick Rule was cancelled in 2007, thereby enabling hedge funds to short shares, i.e. sell shares they did not own, in almost unlimited, immediate quantities, and permitting them to benefit from resultant investor panic in almost any given traded company.

Example: Micro-cap company "X" has designed and patented a revolutionary widget. Recently, the achievements of "X" have made their way into the news, and its shares have risen. Farmer Joe, who attends night school and reads the financial news, decides to buy 1,000 shares of "X". However, Farmer Joe is unaware that Slick Eddy at Hedge Fund "Z", who couldn't care less about the merits of company "X"'s widgets, has also noticed the rise in the share price of "X". With almost unlimited resources behind him, Eddy borrows "X" shares from various financial institutions and begins to sell vast quantities into the market, causing a precipitous decline in the market price of "X". Eddy then blocks any rally in the share price by activating a computerized program to immediately sell 100 shares at the bid after any purchase. Worried by the huge downswing in the price of "X," and also concerned that at the end of each trading day "X" always goes down (Eddy often sells into the market during the last seconds of trading), Farmer Joe dumps his shares at an enormous loss ("Someone must know that something is wrong at 'X'"). Having succeeded in panicking Farmer Joe and other small investors in "X", Eddy buys back the shares at a significantly lower average price than that at which he sold them, resulting in enormous profits for Hedge Fund "Z". Eddy's bosses note his "fine" work and reward him with bonuses as the shares of "X" tumble.

Of course, there are those who will say that ultimately the stock market is "efficient", and the price of "X" will recover to an appropriate level. However, in the process we have witnessed the flow of wealth from Farmer Joe and other small investors to Hedge Fund "Z" and Slick Eddy.

Also, consider the damage to company "X", which, owing to doubt raised by the run on its shares, is suddenly unable to raise additional funds to finance expanded production of a new line of widgets, declares bankruptcy and fires its staff.

Sure, there are instances when the scientific and/or commercial progress of a company shorted by Hedge Fund "Z" is so great that Hedge Fund "Z" must buy back the shares at a higher price, but these losses are more than covered by its programmed downward manipulation of the shares of many other companies.

It is widely thought that the elimination of the Uptick Rule significantly contributed to the 2008 financial crisis from which America has yet to recover. Why has the Uptick Rule not been reinstated? Obviously, there are powerful lobbyists from the financial industry opposed to its reenactment, which would kill this cash cow.

You think that you are "investing" in the stock market? In fact, there are powerful algorithmic forces driving the markets behavior and directly affecting the value of your shares, which have nothing to do with the strength or potential of the companies in which you invest.

Obama wants to reinvigorate the US economy? It is time to reinstate the Uptick Rule, before it becomes too late.

Saturday, February 2, 2013

Roger Cohen, "Israel’s Mr. Normal": Junk Journalism

Roger ("Iran is not totalitarian") Cohen is a sordid journalist, and in his latest New York Times op-ed entitled "Israel’s Mr. Normal" (http://www.nytimes.com/2013/02/03/opinion/sunday/cohen-yair-lapid-israels-mr-normal.html?_r=0), which is devoted to smearing Israeli television host-turned-politician Yair Lapid, Cohen again displays the full extent of his "artistry." Writing from Tel Aviv, Cohen informs us:

"Tom Segev, an Israeli historian, told me that voters who chose Lapid 'decided to vote for nothing, a TV image, a kind of anti-Orthodox Likud lite.'

A ballot cast for nothingness is a curious choice in a nation surrounded by turmoil. Israelis — like the French with François Hollande — went for a Mr. Normal, but a better-looking one. Lapid, a former TV talk-show host and now the second most powerful politician in Israel after Prime Minister Benjamin Netanyahu, is reasonable. He wants everyone to pull their weight, especially the welfare-supported ultra-Orthodox who avoid the draft. He thinks talking to Palestinians is a good idea.

He is also a secular nationalist who made his campaign speech about diplomacy in Ariel, a large West Bank settlement. He is a man who leans right, the darling of the jeep-driving tycoons of start-up-nation Israel who worry more about the country’s battered image than its squeezed youth and middle class, the likes of Yoraan and Anda [a young Jewish immigrant couple with whom Cohen met]. His moderation is more aura than anything."

Well, let's give this some thought. A vote for Lapid was a "vote for nothing," because Tom Segev, a historian and journalist who writes a column for Israel's leftist Haaretz newspaper, told him so?

Why didn't Cohen trouble himself to interview Lapid?

Why didn't Cohen trouble himself to interview any of the other leaders of Lapid's new party, "Yesh Atid" ("There Is a Future")?

Why didn't Cohen trouble himself to learn more about "Yesh Atid" by at least looking at their website? Oops, I forgot: Cohen doesn't read Hebrew.

But wait! Yesh Atid also has an English website (http://en.yeshatid.org.il/team), where details are provided concerning the impressive and diverse backgrounds of its new members of parliament, who include many women, two Ethiopian Jews, and a former head of Israel's General Security Service.

Lapid's "moderation is more aura than anything"? Peculiar how Cohen doesn't mention that Yair Lapid is the son of Tommy Lapid, who headed Israel's secular-liberal "Shinui" ("Change") party from 1999–2006.

Bottom line: This op-ed is junk journalism to which Cohen's New York Times readership is addicted.